In this working paper, we describe Israel’s innovation ecosystem. As a country widely described as the Start-Up Nation (Senor & Singer, 2011), there is considerable interest in the system and forces that drive Israel’s vigorous entrepreneurship. We begin by presenting the key anchors and processes of Israeli innovation that emerged from the Experts Workshop, along with the cross-impact analysis showing how they are inter-related. To concretize this analysis, we describe in detail some of the main programs in the innovation ecosystem. Finally, the visualization of Israel’s innovation ecosystem is presented and discussed.